![]() ![]() Bilirubin concentration in the drainage fluid on postoperative day 2 is a strong predictor of clinically relevant bile leakage.Ĭopyright © 2012 Mosby, Inc. The ISGLS definition and severity grading of bile leakage after hepatic resection is clinically meaningful. 04) as independent predictors of clinically relevant bile leakage. ![]() Stress results in fluid buildup and inflammation near loose joints. Peritoneal drains are placed after elective colorectal surgery in the historical belief that they can provide diagnostic and therapeutic benefit through prevention and early detection of anastomotic leak or other intraperitoneal collections 1, 2. The American Academy of Orthopaedic Surgeons says athletic activities loosen small particles referred to as wear debris in the joint, causing pain and fluid buildup 2. Multivariate analysis confirmed bilirubin concentration in the drainage fluid ≥2.4 mg/dL on postoperative day 2 (odds ratio 11.88 95% confidence interval 5.33-26.49 P <. Fluid buildup occurs after knee replacement surgery with increased wear and tear. Perioperative mortality was 0% for Grade A, 5.2% for Grade B, and 45.4% for Grade C bile leakage (P <. The definition as well as severity grading of bile leakage correlated with the duration of drainage and intensive care unit and hospital stay. Grade A, B, and C bile leakage was diagnosed in 23 (8.7%), 38 (14.3%), and 11 (4.1%) patients, respectively. Risk factors of Grade B/C bile leakage were assessed by the use of univariate and multivariate analyses. Bilirubin concentrations were determined in the serum and drainage fluid until postoperative day 5. Furthermore, we sought to identify early predictors of clinically relevant bile leakage.Ī total of 265 patients who underwent elective hepatic resection were enrolled prospectively. It was our aim in the present study to prospectively validate the ISGLS definition of bile leakage after hepatic resection. Most physical wounds produce some drainage. The International Study Group of Liver Surgery (ISGLS) definition standardizes reporting of this complication. Serosanguineous is the term used to describe discharge that contains both blood and a clear yellow liquid known as blood serum. Variations in the definition of bile leakage after hepatic resection have prevented the identification of risk factors for early diagnosis and efficient management. ![]()
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